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Abdominal migraine

MedGen UID:
124374
•Concept ID:
C0270858
•
Disease or Syndrome
Synonyms: Abdominal Migraine; Abdominal Migraines; Migraine, Abdominal; Migraines, Abdominal
SNOMED CT: Abdominal migraine (75879005); Decapitated migraine (75879005)

Definition

Paroxysmal episodes of intense, acute periumbilical pain that lasts for one or more hours with intervening periods of usual health lasting weeks to months, with no evidence of an inflammatory, anatomic, metabolic, or neoplastic process that explains the symptoms. The pain interferes with normal activities and is associated with at least two of the following symptoms: anorexia, nausea, vomiting, headache, photophobia, and/or pallor. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbdominal migraine

Professional guidelines

PubMed

Probiotics for management of functional abdominal pain disorders in children.
Wallace C, Gordon M, Sinopoulou V, Akobeng AK
Cochrane Database Syst Rev 2023 Feb 17;2(2):CD012849. doi: 10.1002/14651858.CD012849.pub2. PMID: 36799531Free PMC Article
Non-pharmacological management of abdominal pain-related functional gastrointestinal disorders in children.
Paul SP, Basude D
World J Pediatr 2016 Nov;12(4):389-398. Epub 2016 Jun 30 doi: 10.1007/s12519-016-0044-8. PMID: 27363985
Pediatric migraine variants: a review of epidemiology, diagnosis, treatment, and outcome.
Lagman-Bartolome AM, Lay C
Curr Neurol Neurosci Rep 2015 Jun;15(6):34. doi: 10.1007/s11910-015-0551-3. PMID: 25903296

Recent clinical studies

Etiology

Probiotics for management of functional abdominal pain disorders in children.
Wallace C, Gordon M, Sinopoulou V, Akobeng AK
Cochrane Database Syst Rev 2023 Feb 17;2(2):CD012849. doi: 10.1002/14651858.CD012849.pub2. PMID: 36799531Free PMC Article
Abdominal migraine.
Angus-Leppan H, Saatci D, Sutcliffe A, Guiloff RJ
BMJ 2018 Feb 19;360:k179. doi: 10.1136/bmj.k179. PMID: 29459383
Recurrent Gastrointestinal Disturbance: Abdominal Migraine and Cyclic Vomiting Syndrome.
Irwin S, Barmherzig R, Gelfand A
Curr Neurol Neurosci Rep 2017 Mar;17(3):21. doi: 10.1007/s11910-017-0731-4. PMID: 28283964
Lifestyle Factors and Migraine in Childhood.
Russo A, Bruno A, Trojsi F, Tessitore A, Tedeschi G
Curr Pain Headache Rep 2016 Feb;20(2):9. doi: 10.1007/s11916-016-0539-y. PMID: 26757711
Childhood functional gastrointestinal disorders: child/adolescent.
Rasquin A, Di Lorenzo C, Forbes D, Guiraldes E, Hyams JS, Staiano A, Walker LS
Gastroenterology 2006 Apr;130(5):1527-37. doi: 10.1053/j.gastro.2005.08.063. PMID: 16678566Free PMC Article

Diagnosis

Abdominal migraine and cyclical vomiting syndrome.
Cheema S, Matharu M
Handb Clin Neurol 2023;198:209-219. doi: 10.1016/B978-0-12-823356-6.00006-8. PMID: 38043963
Paediatric functional abdominal pain disorders.
Thapar N, Benninga MA, Crowell MD, Di Lorenzo C, Mack I, Nurko S, Saps M, Shulman RJ, Szajewska H, van Tilburg MAL, Enck P
Nat Rev Dis Primers 2020 Nov 5;6(1):89. doi: 10.1038/s41572-020-00222-5. PMID: 33154368
Managing cyclic vomiting syndrome in children: beyond the guidelines.
Li BUK
Eur J Pediatr 2018 Oct;177(10):1435-1442. Epub 2018 Aug 3 doi: 10.1007/s00431-018-3218-7. PMID: 30076469Free PMC Article
Abdominal migraine.
Angus-Leppan H, Saatci D, Sutcliffe A, Guiloff RJ
BMJ 2018 Feb 19;360:k179. doi: 10.1136/bmj.k179. PMID: 29459383
Childhood functional gastrointestinal disorders: child/adolescent.
Rasquin A, Di Lorenzo C, Forbes D, Guiraldes E, Hyams JS, Staiano A, Walker LS
Gastroenterology 2006 Apr;130(5):1527-37. doi: 10.1053/j.gastro.2005.08.063. PMID: 16678566Free PMC Article

Therapy

Probiotics for management of functional abdominal pain disorders in children.
Wallace C, Gordon M, Sinopoulou V, Akobeng AK
Cochrane Database Syst Rev 2023 Feb 17;2(2):CD012849. doi: 10.1002/14651858.CD012849.pub2. PMID: 36799531Free PMC Article
Managing cyclic vomiting syndrome in children: beyond the guidelines.
Li BUK
Eur J Pediatr 2018 Oct;177(10):1435-1442. Epub 2018 Aug 3 doi: 10.1007/s00431-018-3218-7. PMID: 30076469Free PMC Article
Recurrent Gastrointestinal Disturbance: Abdominal Migraine and Cyclic Vomiting Syndrome.
Irwin S, Barmherzig R, Gelfand A
Curr Neurol Neurosci Rep 2017 Mar;17(3):21. doi: 10.1007/s11910-017-0731-4. PMID: 28283964
Lifestyle Factors and Migraine in Childhood.
Russo A, Bruno A, Trojsi F, Tessitore A, Tedeschi G
Curr Pain Headache Rep 2016 Feb;20(2):9. doi: 10.1007/s11916-016-0539-y. PMID: 26757711
Abdominal migraine.
Napthali K, Koloski N, Talley NJ
Cephalalgia 2016 Sep;36(10):980-6. Epub 2015 Nov 17 doi: 10.1177/0333102415617748. PMID: 26582952

Prognosis

Abdominal migraine and cyclical vomiting syndrome.
Cheema S, Matharu M
Handb Clin Neurol 2023;198:209-219. doi: 10.1016/B978-0-12-823356-6.00006-8. PMID: 38043963
Recurrent Gastrointestinal Disturbance: Abdominal Migraine and Cyclic Vomiting Syndrome.
Irwin S, Barmherzig R, Gelfand A
Curr Neurol Neurosci Rep 2017 Mar;17(3):21. doi: 10.1007/s11910-017-0731-4. PMID: 28283964
Non-pharmacological management of abdominal pain-related functional gastrointestinal disorders in children.
Paul SP, Basude D
World J Pediatr 2016 Nov;12(4):389-398. Epub 2016 Jun 30 doi: 10.1007/s12519-016-0044-8. PMID: 27363985
Migraine Variants or Episodic Syndromes That May Be Associated With Migraine and Other Unusual Pediatric Headache Syndromes.
Rothner AD, Parikh S
Headache 2016 Jan;56(1):206-14. doi: 10.1111/head.12750. PMID: 26790855
Migraine equivalents in childhood.
Teixeira KC, Montenegro MA, Guerreiro MM
J Child Neurol 2014 Oct;29(10):1366-9. Epub 2013 Oct 3 doi: 10.1177/0883073813504459. PMID: 24092892

Clinical prediction guides

Neonatal Antibiotics and Food Allergy Are Associated With FGIDs at 4-6 Years of Age.
Kamphorst K, Vlieger AM, Oosterloo BC, Garssen J, van Elburg RM
J Pediatr Gastroenterol Nutr 2022 Jun 1;74(6):770-775. Epub 2022 Feb 24 doi: 10.1097/MPG.0000000000003428. PMID: 35588166
Behavioral Intervention in Children with Functional Abdominal Pain Disorders: A Promising Option.
Saini S, Narang M, Srivastava S, Shah D
Turk J Gastroenterol 2021 May;32(5):443-450. doi: 10.5152/tjg.2021.20679. PMID: 34231474Free PMC Article
Prevalence of abdominal migraine and recurrent abdominal pain in a Japanese clinic.
Hikita T
Pediatr Int 2016 Jul;58(7):669-71. doi: 10.1111/ped.13005. PMID: 27460403
Abdominal migraine in children: association between gastric motility parameters and clinical characteristics.
Devanarayana NM, Rajindrajith S, Benninga MA
BMC Gastroenterol 2016 Feb 29;16:26. doi: 10.1186/s12876-016-0435-2. PMID: 26924750Free PMC Article
Abdominal migraine: an under-diagnosed cause of recurrent abdominal pain in children.
Carson L, Lewis D, Tsou M, McGuire E, Surran B, Miller C, Vu TA
Headache 2011 May;51(5):707-12. Epub 2011 Mar 11 doi: 10.1111/j.1526-4610.2011.01855.x. PMID: 21395574

Recent systematic reviews

Probiotics for management of functional abdominal pain disorders in children.
Wallace C, Gordon M, Sinopoulou V, Akobeng AK
Cochrane Database Syst Rev 2023 Feb 17;2(2):CD012849. doi: 10.1002/14651858.CD012849.pub2. PMID: 36799531Free PMC Article
Pharmacological interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood.
Huertas-Ceballos A, Logan S, Bennett C, Macarthur C
Cochrane Database Syst Rev 2008 Jan 23;(1):CD003017. doi: 10.1002/14651858.CD003017.pub2. PMID: 18254013
Systematic review of treatments for recurrent abdominal pain.
Weydert JA, Ball TM, Davis MF
Pediatrics 2003 Jan;111(1):e1-11. doi: 10.1542/peds.111.1.e1. PMID: 12509588
Pharmacological interventions for recurrent abdominal pain (RAP) in childhood.
Huertas-Ceballos A, Macarthur C, Logan S
Cochrane Database Syst Rev 2002;(1):CD003017. doi: 10.1002/14651858.CD003017. PMID: 11869650

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